Difference between revisions of "HIV transcription"
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The proviral DNA contains all of the signals necessary to support transcription of the viral genome mediated by the host cell RNA polymerase II. The viral long terminal repeat (LTR) binds a variety of cellular transcription factors, including the host cell encoded NFkappaB heterodimer <ref> [http://www.ncbi.nlm.nih.gov/pubmed?term=An%20inducible%20transcription%20factor%20activates%20expression%20of%20human%20immunodeficiency%20virus%20in%20T%20cells Nabel G, Baltimore D. 1987. An inducible transcription factor activates expression of human immunodeficiency virus in T cells. Nature 326: 711-713.] </ref> | The proviral DNA contains all of the signals necessary to support transcription of the viral genome mediated by the host cell RNA polymerase II. The viral long terminal repeat (LTR) binds a variety of cellular transcription factors, including the host cell encoded NFkappaB heterodimer <ref> [http://www.ncbi.nlm.nih.gov/pubmed?term=An%20inducible%20transcription%20factor%20activates%20expression%20of%20human%20immunodeficiency%20virus%20in%20T%20cells Nabel G, Baltimore D. 1987. An inducible transcription factor activates expression of human immunodeficiency virus in T cells. Nature 326: 711-713.] </ref> | ||
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Revision as of 16:23, 18 October 2011
The proviral DNA contains all of the signals necessary to support transcription of the viral genome mediated by the host cell RNA polymerase II. The viral long terminal repeat (LTR) binds a variety of cellular transcription factors, including the host cell encoded NFkappaB heterodimer [1]
