Lentiviral particles

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Lentiviral particles

Introduction Lentiviral proteins

This figure shows a drawing of a lentiviral particle, generated by assembling envelopes from X-ray structures of individual proteins.

A lentiviral particle. Structures used to assemble the particle were from Liu et al. 2008 [1]; Alfadhli et al. 2009[2]; Pornillos et al. 2009.[3]

The colors assigned here are preserved in the other images in this review. Table 1 summarizes the viral proteins and the color scheme.

  1. Liu J, Bartesaghi A, Borgnia MJ, Sapiro G, Subramaniam S. 2008. Molecular architecture of native HIV-1 gp120 trimers. Nature 455: 109-113.
  2. Alfadhli A, Barklis RL, Barklis E. 2009. HIV-1 matrix organizes as a hexamer of trimers on membranes containing phosphatidylinositol-(4,5)-bisphosphate. Virology 387: 466-472.
  3. Pornillos O, Ganser-Pornillos BK, Kelly BN, Hua Y, Whitby FG, Stout CD, Sundquist WI, Hill CP, Yeager M. 2009. X-ray structures of the hexameric building block of the HIV capsid. Cell 137: 1282-1292.